Spend $99, get free U.S. shipping*
Tariff now required on U.S. shipments. Learn more »
Tel: 1-866-456-3768 Fax: 1-866-544-8993
For visual reference only; actual product may vary
For visual reference only; actual product may vary
Breztri Aerosphere is a daily maintenance inhaler for adults with moderate to severe COPD. It combines three active ingredients (budesonide, glycopyrronium, and formoterol) to reduce airway inflammation and help you breathe easier. Take control of your COPD symptoms with this effective triple-therapy treatment.
| Trixeo Aerosphere Brand | 5mcg/7.2mcg/160mcg 120 Doses |
-
|
Our price: $133.00 |
Breztri Aerosphere is a prescription maintenance inhaler used for the long-term management of chronic obstructive pulmonary disease (COPD) in adults. It is a triple-therapy medication, meaning it combines three different active ingredients—budesonide, glycopyrronium, and formoterol fumarate—into a single metered-dose inhaler. Breztri is intended for daily use to help control symptoms and prevent flare-ups, but it is not a rescue inhaler and should not be used for sudden breathing problems. The same combination of ingredients is sold in other markets under the name Trixeo Aerosphere.
Breztri works through the combined action of its three ingredients to improve breathing in patients with COPD. Two of the ingredients, glycopyrronium (a LAMA) and formoterol (a LABA), are bronchodilators that work by relaxing and opening up the muscles around the airways, making it easier to breathe. The third ingredient, budesonide, is an inhaled corticosteroid (ICS) that reduces inflammation in the lungs. This triple-action approach provides comprehensive management of COPD by both widening the airways and controlling the underlying inflammation that can cause them to narrow, leading to fewer symptoms and a lower risk of severe flare-ups.
Breztri is for adults who have been diagnosed with moderate to severe COPD and require a more advanced level of maintenance treatment. It is typically prescribed when a patient’s symptoms are not adequately controlled by a combination of just one or two types of long-acting medications. Breztri is not intended for the treatment of asthma. A firm diagnosis of COPD from a healthcare provider, often confirmed by a breathing test called spirometry, is necessary before starting this medication. Patients prescribed Breztri should also have a separate rescue inhaler, like albuterol, for any sudden onset of breathing difficulties.
The standard dosage for Breztri Aerosphere is two inhalations taken twice per day, once in the morning and once in the evening. For the medication to be effective, it must be used every day as prescribed, even if you are feeling well. To use the inhaler, shake it well, exhale fully, place the mouthpiece in your mouth, and begin to breathe in slowly and deeply as you press down on the canister. Hold your breath for up to 10 seconds, then exhale slowly. To prevent oral thrush, a common side effect, it is critical to rinse your mouth with water and spit it out after each dose.
While many people using Breztri experience significant benefits with no issues, some side effects can occur. The most common side effects include upper respiratory tract infections, pneumonia, headache, oral thrush (a fungal infection in the mouth), cough or hoarse voice, muscle cramps, and palpitations. More serious side effects can include severe allergic reactions. Rinsing your mouth after use helps prevent thrush. If you experience any severe or persistent side effects, such as worsening breathing, vision changes, or signs of an infection like a fever, consult your doctor immediately.
IsraelPharm is a trusted source for authentic, high-quality medications at affordable prices. We believe that managing chronic conditions like COPD shouldn’t be a financial burden. By sourcing medications from a regulated supply chain, we can offer prescription drugs like Breztri at lower costs. Our licensed pharmacists are available to answer your questions, and our user-friendly online platform makes ordering your medication simple and convenient. Choose IsraelPharm for reliable service and significant savings on your long-term healthcare needs.
This information is for guidance only. Always consult your doctor or pharmacist about the potential side effects of any medication. Your doctor has prescribed Breztri because they have judged that the benefit to you is greater than the risk of side effects.
Seek immediate medical attention if you experience signs of a severe allergic reaction, such as swelling of the face, tongue or throat; difficulty breathing or swallowing; rash; hives; or sudden wheezing after your dose.
Common side effects of Breztri may include:
This is not a complete list. If you experience these or any other concerning symptoms that persist or worsen, contact your healthcare provider.
Breztri (budesonide/glycopyrronium/formoterol) is a long-term maintenance treatment prescribed for adults with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).
It is designed to help manage and prevent the common symptoms of COPD, including:
By controlling these symptoms, Breztri also helps reduce the frequency of flare-ups (exacerbations), which can lead to serious lung infections like acute bronchitis or pneumonia.
Breztri is a long-term, daily maintenance medication used to manage symptoms and reduce flare-ups in adults with moderate to severe Chronic Obstructive Pulmonary Disease (COPD). It is not used for asthma or for immediate relief of sudden breathing problems. For acute symptoms, you should use a rescue inhaler as prescribed by your doctor.
No, Breztri is a maintenance inhaler, not a rescue inhaler. It is designed for long-term, daily use to manage COPD symptoms and prevent flare-ups over time. It does not provide immediate relief from sudden breathing attacks. Always keep a fast-acting rescue inhaler with you for emergencies as directed by your healthcare provider.
Breztri's effects build over time with consistent daily use. While formoterol, one of its components, has a relatively fast onset of action to help open airways, the full benefit for reducing inflammation and preventing flare-ups may take several days to weeks of regular, twice-daily use. It is designed for long-term control, not rapid, on-the-spot relief.
It is very important to rinse your mouth with water and spit it out after each dose of Breztri. This action helps remove any leftover medication from your mouth and throat, significantly reducing your risk of developing a fungal infection called oral thrush (candidiasis), which is a common side effect of inhaled corticosteroids like budesonide.
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and resume your regular dosing schedule. Do not take two doses at the same time or extra doses to make up for the one you missed. Consistency is key to managing COPD effectively.
Breztri contains three active ingredients. Budesonide is an inhaled corticosteroid that reduces inflammation in the airways. Glycopyrronium is a long-acting muscarinic antagonist (LAMA) and formoterol is a long-acting beta2-agonist (LABA). The latter two are bronchodilators that relax airway muscles to make breathing easier. This is why it is called a "triple-therapy" inhaler.
The Breztri Aerosphere inhaler comes with a dose counter on the top, which shows how many inhalations are left. The number will decrease after each puff. You should order a refill when the number gets low, and you must discard the inhaler when the counter shows "0," even if it feels like there is still medicine inside.
You should store your Breztri inhaler at a controlled room temperature, away from direct sunlight, extreme heat, and high humidity. Keep the cap on the mouthpiece when not in use. Do not puncture the canister or store it near an open flame, as its contents are under pressure. Keep it out of reach of children.
While moderate alcohol consumption is not strictly forbidden, it can sometimes worsen side effects like dizziness or interact with your overall health. Alcohol can also impact your breathing. It is always best to discuss your alcohol use with your doctor to understand any potential risks based on your personal health condition and other medications you may be taking.
Weight gain is a possible side effect of oral corticosteroids, but it is less common with inhaled corticosteroids like the budesonide in Breztri because the drug acts directly in the lungs with less systemic absorption. However, some individuals may still experience changes in weight. If you notice significant, unexplained weight gain, discuss it with your healthcare provider.
Yes, because Breztri contains an inhaled corticosteroid (budesonide), it can slightly increase the risk of developing lung infections like pneumonia. It is important to report any signs of infection, such as fever, chills, increased cough, or changes in mucus color, to your doctor right away. Rinsing your mouth can help prevent oral infections.
Breztri is not approved by the FDA for the treatment of asthma. Its safety and effectiveness have been established for the long-term maintenance treatment of COPD in adults. Using it for asthma could lead to improper management of the condition and potential health risks. You should only use Breztri as prescribed by your doctor for your specific condition.
Before starting Breztri, inform your doctor of all other medications you take, including prescriptions, over-the-counter drugs, and supplements. Be particularly mindful of other long-acting bronchodilators, certain antibiotics, antifungals, and antidepressants. Combining medications can sometimes increase the risk of side effects, such as heart-related issues, so a full review by your doctor is essential.
Yes, you need to shake the Breztri inhaler well for at least five seconds before each inhalation. This step is crucial to ensure that the three active ingredients are properly mixed together. Shaking the canister helps guarantee that you receive a consistent and effective dose of the medication with every puff you take.
You should not stop using Breztri suddenly, even if you start to feel better. COPD is a chronic condition that requires continuous treatment. Stopping your maintenance medication can lead to a return or worsening of your symptoms and increase your risk of a serious flare-up. Always consult your doctor before making any changes to your treatment plan.
Send Your Prescription
No Hidden Fees
Generally 7-10 Business Days
IsraelPharm has been delivering lost cost prescriptions from Israel for over 15 years worldwide. Daily flights allow us to get your medications dispatched fast! Delivery to the USA is under 10 days and you can track and trace every order.
For many years, managing type 2 diabetes (T2D) felt like a single-minded pursuit: get the blood sugar down. While crucial, this approach overlooked a more dangerous threat. People with type 2 diabetes are far more
In the world of psoriatic arthritis (PsA) treatments, a new head-to-head comparison has generated significant discussion. A recent study directly comparing Bimzelx and Skyrizi showed that for the primary goal of joint improvement, Bimzelx outperformed
The announcement on May 1st, 2026, that Jakafi XR has been approved by the FDA for patients managing myelofibrosis offers a new dosing option . Prior to this announcement, Jakafi was widely used in treatment
