Ibsrela (
generic name: tenapanor) is a prescription medication specifically designed to treat adults with
irritable bowel syndrome with constipation (
IBS-C).
Tenapanor works by inhibiting the sodium/hydrogen exchanger 3 (NHE3) in the small intestine. This reduces the absorption of sodium, leading to increased intestinal water secretion, which softens stools and makes them easier to pass. By acting directly on the gut, Ibsrela can
alleviate the discomfort, bloating, and constipation often associated with IBS-C, providing patients with a targeted treatment option for managing symptoms.
Unlike traditional laxatives that address constipation by triggering bowel movements, Ibsrela tackles the underlying mechanisms in the intestine, leading to a more regulated digestive process. Tenapanor is generally well-tolerated and may be prescribed to patients who have not responded adequately to other treatments. Another drug in the same category is
Linzess, which is also commonly used to treat IBS-C.
For more detailed information about Ibsrela and its use in treating IBS-C, visit
this external source.
Dosage
Patients should follow the prescribing healthcare provider’s instructions and avoid altering the dose or skipping doses without consulting their doctor. The usual recommended dosage of Ibsrela is 50 mg twice daily, immediately before breakfast and dinner. For optimal effectiveness, it is important to take the medication on an empty stomach.
Storage
Store Ibsrela at room temperature (20°-25°C/68°-77°F) in its original packaging, tightly sealed, and out of reach of children. Avoid exposure to excessive moisture or heat. If there are any questions, read
our blog on safe medicine management.
Common Questions About Ibsrela
How long does it take for Ibsrela to work?
Ibsrela can begin to relieve IBS-C symptoms, such as constipation, within the first week of starting treatment. However, the exact response time varies between individuals. Some patients may notice improvements sooner, while for others it may take a bit longer. It’s important to continue taking the medication as prescribed and consult with a healthcare provider if there are any concerns about how quickly it’s working.
Can Ibsrela be taken with food?
It is best to take Ibsrela twice daily before meals—once before breakfast and once before dinner. Taking Ibsrela on an empty stomach ensures that it works effectively. Avoid taking the medication with food, as doing so may reduce its efficacy.
Can Ibsrela cause diarrhea?
Yes, Ibsrela may cause diarrhea in some patients. While diarrhea is a common side effect, it can sometimes be severe and lead to dehydration. If you experience persistent or severe diarrhea while taking Ibsrela, contact a healthcare provider of pharmacist for guidance on whether to continue the treatment.
This text is for informational purposes only. Please consult a doctor or pharmacist before using any medication.
Read the information leaflet that comes with the medication.
Most people who use Ibsrela do not experience any adverse side effects. Doctors prescribe this medication because they assess the benefits of such treatment outweigh any likely unwanted effects.
Some of the side effects that have been reported include:
- Diarrhea
- Abdominal pain
- Bloating
- Gas
Caution:
Severe diarrhea can lead to dehydration. If persistent diarrhea occurs, patients should stop taking Ibsrela and contact their healthcare provider immediately.
Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult a healthcare provider or pharmacist.
Ibsrela is FDA-approved for the treatment of Irritable Bowel Syndrome with Constipation (IBS-C).
IBS-C is a common gastrointestinal disorder characterized by abdominal pain, bloating, and infrequent, difficult-to-pass stools. Ibsrela works by increasing fluid in the gut to ease stool passage and reduce the discomfort associated with constipation.
Symptoms of IBS-C that Ibsrela treats include abdominal pain, bloating, and infrequent bowel movements that are often hard or painful to pass