This text is for informational purposes only. Please consult with a doctor or pharmacist before using any medication.

Mild side effects may include:

• insomnia
• dizziness
• drowsiness
• headache
• diarrhea
• nausea
• dry mouth
• ejaculation failure
• fatigue
• flu-like symptoms (chest cold, sore throat, runny nose)
• changes in appetite
• increased anxiety, depression, agitation, decreased sexual interest, nervousness, feeling strange, nightmares, teeth grinding when sleeping
• tremors
• muscular movement disorders
• ear pain.

Not all side effects are listed here. If these or other unlisted symptoms persist or worsen, consult with a healthcare provider or pharmacist.

There are some less common but potentially serious side effects that can occur. Report to a doctor immediately if:

• there are symptoms of depression with thoughts of self-harm or suicidal thoughts
• a severe skin rash that leads to the onset of blisters, (sometimes also on the mouth and tongue) develops. These may be symptoms of Stevens-Johnson syndrome or Toxic Epidermal Necrolysis
• there are feelings of agitation, confusion, diarrhea, high temperature, rise in blood pressure, excessive sweating and rapid heartbeat, they could be symptoms of serotonin syndrome
• the skin and whites of the eyes turn yellow, which may be indicative of liver damage.

If a sudden allergic reaction (anaphylaxis) such as swelling of the face, tongue or throat makes it difficult to breathe or swallow, or there is wheezing, hives, rash, or sloughing of the skin, call a doctor or 911 right away, or go to an emergency room immediately.

The symptoms of conditions like depression, obsessive-compulsive disorder (OCD), panic disorder, premenstrual dysphoric disorder (PMDD), post-traumatic stress disorder (PTSD), and social anxiety disorder (SAD) are often associated with low levels of serotonin. Serotonin is the body’s natural “feel good” hormone that regulates mood. When serotonin is at normal levels, a person will feel focused, emotionally stable, happier, and calmer. 

Lustral / Zoloft is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels in the brain by inhibiting the reuptake of the hormone.